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Mitochondria may hold the key to curing diabetes

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Professor David Ray鈥檚 laboratory in the Department of Biological Sciences helped identify genetic components in bats that provide insight into their immune systems.

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Credit: Adobe Stock A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the聽Johns Hopkins Kimmel Cancer Center聽Bloomberg~Kimmel Institute for Cancer Immunotherapy聽and the聽Johns Hopkins University School of Medicine.

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As one of the largest tuberculosis outbreaks in the U.S. unfolds in Kansas, UC San Diego researchers and their colleagues have published research describing the use of artificial intelligence tools to screen for new antimicrobial candidates to treat the disease.

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When life gets bleak for Destany Epps-Manuel, 36, she knows the only way to go is forward. That鈥檚 what she鈥檚 been doing since she was 22, when she was diagnosed with dilated cardiomyopathy, a rare disease that causes the heart muscle to weaken and, eventually, stop pumping blood.

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Nearly every disease has an inflammatory component, but blood tests can鈥檛 pinpoint inflammation in specific organs or tissues in the human body.

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Investigadores de Mayo Clinic han sido pioneros en una herramienta de inteligencia artificial (IA) llamada OmicsFootPrint, que ayuda a convertir grandes cantidades de datos biol贸gicos complejos en im谩genes circulares bidimensionales. Los detalles de la herramienta se publicaron en un estudio en Nucleic Acids Research.

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Pesquisadores da Mayo Clinic foram pioneiros em uma ferramenta de intelig锚ncia artificial (IA) chamada OmicsFootPrint, que ajuda a converter grandes quantidades de dados biol贸gicos complexos em imagens circulares bidimensionais. Os detalhes da ferramenta foram publicados em um estudo na Nucleic Acids Research.

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Mayo Clinic researchers have pioneered an artificial intelligence (AI) tool, called OmicsFootPrint, that helps convert vast amounts of complex biological data into two-dimensional circular images. The details of the tool are published in a study in Nucleic Acids Research.

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A new study from the Hong Kong Children's Hospital reveals critical insights into the infection risks associated with pediatric allogeneic hematopoietic stem cell transplantation (HSCT). The research identifies key risk factors that influence infection timelines and outcomes, offering a pathway toward more effective, personalized prevention strategies.

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A nasal vaccine for COVID-19 鈥� based on technology developed at Washington University in St. Louis 鈥� is poised to enter a phase 1 clinical trial in the U.S.

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Set to enter hospice care, a patient with idiopathic multicentric Castleman鈥檚 disease is now in remission after treatment with a medication identified by an AI-guided analysis

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Over the past decade, chimeric antigen receptor (CAR) T-cell therapy has revolutionized treatment for children with B-cell acute lymphoblastic leukemia (ALL). But unfortunately, CAR T-cells have been far less effective for another blood cancer: acute myeloid leukemia (AML).

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Dana-Farber Cancer Institute researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney cancer), generated a successful anti-cancer immune response after initiation of a personalized cancer vaccine.

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Personalized cancer vaccines (PCVs) train the body鈥檚 immune system to recognize and destroy a threat. In this trial, all nine patients who received multiple doses of the vaccine had an immune response within a three-week period and cancer fighting T cells remained elevated for the duration of the study and for years afterward.

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Children鈥檚 National, ranked among the nation鈥檚 top pediatric hospitals, and Virginia Tech, a nationally leading academic research university, aim to deliver transformative advancements to enhance outcomes for children facing devastating cancer diagnoses.