Latest news from Nature Communications on 海角社区 en-us Copyright 2025 海角社区 115 31 / /images/newswise-logo-rss.gif /articles/spatial-epitranscriptomics-reveals-a-to-i-editome-specific-to-cancer-nbsp-stem-cell-nbsp-microniches/?sc=rsin /articles/spatial-epitranscriptomics-reveals-a-to-i-editome-specific-to-cancer-nbsp-stem-cell-nbsp-microniches/?sc=rsin Fri, 13 May 2022 05:45:10 EST ... With Select-seq, we analyse the cancer聽stem聽cell-like microniches in relation to the tumour microenvironment of triple-negative breast cancer patients. We identify alternative splice variants, perform complementarity-determining region analysis of聽... Nature Communications /articles/a-foxa2-long-term-nbsp-stem-cell-nbsp-population-is-necessary-for-growth-plate-cartilage-regeneration-after-injury/?sc=rsin /articles/a-foxa2-long-term-nbsp-stem-cell-nbsp-population-is-necessary-for-growth-plate-cartilage-regeneration-after-injury/?sc=rsin Tue, 10 May 2022 05:00:53 EST ... reside in the RZ, a known location for stem cells 5,11 , and that FoxA2+ cells are located in close proximity to the SOC, which is viewed as a signaling center of RZ stemness 10 , we asked whether FoxA2+ cells are different than the previously聽... Nature Communications /articles/an-instantly-fixable-and-self-adaptive-scaffold-for-skull-regeneration-by-autologous-nbsp-stem-cell-nbsp-recruitment-and-angiogenesis/?sc=rsin /articles/an-instantly-fixable-and-self-adaptive-scaffold-for-skull-regeneration-by-autologous-nbsp-stem-cell-nbsp-recruitment-and-angiogenesis/?sc=rsin Tue, 10 May 2022 05:00:10 EST Limited stem cells, poor stretchability and mismatched interface fusion have plagued the reconstruction of cranial defects by cell-free scaffolds. Here, we designed an instantly fixable and self-adaptive scaffold by dopamine-modified hyaluronic acid聽... Nature Communications /articles/ascl1-activates-neuronal-nbsp-stem-cell-like-lineage-programming-through-remodeling-of-the-chromatin-landscape-in-prostate-cancer/?sc=rsin /articles/ascl1-activates-neuronal-nbsp-stem-cell-like-lineage-programming-through-remodeling-of-the-chromatin-landscape-in-prostate-cancer/?sc=rsin Mon, 02 May 2022 08:00:40 EST ... ASCL1 is required to establish the neuronal and聽stem聽cell-like lineage ... To determine whether ASCL1 is required for the development of neuronal and聽stem聽cell-like phenotype... neuronal and聽stem聽cell聽differentiation and functions to bias the cell fate聽... Nature Communications /articles/znf117-regulates-glioblastoma-nbsp-stem-cell-nbsp-differentiation-towards-oligodendroglial-lineage/?sc=rsin /articles/znf117-regulates-glioblastoma-nbsp-stem-cell-nbsp-differentiation-towards-oligodendroglial-lineage/?sc=rsin Mon, 25 Apr 2022 04:00:19 EST ... d聽Stem聽cell聽frequency of GS5 cells treated with Cas9 and the indicated sgRNAs as determined by limiting dilution assay. e-g Representative flow cytometry images (e) and corresponding quantification (f) (n = 3 biologically independent samples, black聽... Nature Communications /articles/differential-effects-of-macrophage-subtypes-on-sars-cov-2-infection-in-a-human-pluripotent-nbsp-stem-cell-derived-model/?sc=rsin /articles/differential-effects-of-macrophage-subtypes-on-sars-cov-2-infection-in-a-human-pluripotent-nbsp-stem-cell-derived-model/?sc=rsin Mon, 25 Apr 2022 02:10:35 EST ... In this study, we generate lung cells and macrophages from the same human pluripotent聽stem聽cell聽(hPSC) lines and pair them to establish a co-culture system. This strategy addresses a common concern about histocompatibility when studying聽... Nature Communications /articles/astroblastomas-exhibit-radial-glia-nbsp-stem-cell-nbsp-lineages-and-differential-expression-of-imprinted-and-x-inactivation-escape-genes/?sc=rsin /articles/astroblastomas-exhibit-radial-glia-nbsp-stem-cell-nbsp-lineages-and-differential-expression-of-imprinted-and-x-inactivation-escape-genes/?sc=rsin Mon, 25 Apr 2022 02:10:30 EST ... ABCC1 encodes the ATPase cassette transporter protein multidrug resistance 1, a聽stem聽cell聽marker and MYCN transcriptional target conferring ... 1, 2), suggesting they share a common ependymal聽stem聽cell聽lineage. The mismatch repair gene聽... Nature Communications /articles/single-cell-analyses-identify-a-highly-regenerative-and-homogenous-human-cd34-hematopoietic-nbsp-stem-cell-nbsp-population/?sc=rsin /articles/single-cell-analyses-identify-a-highly-regenerative-and-homogenous-human-cd34-hematopoietic-nbsp-stem-cell-nbsp-population/?sc=rsin Mon, 25 Apr 2022 02:10:16 EST The heterogeneous nature of human CD34+ hematopoietic stem cells (HSCs) has hampered our understanding of the cellular and molecular trajectories that HSCs navigate during lineage commitment. Using various platforms including single cell聽... Nature Communications /articles/cpeb1-directs-muscle-nbsp-stem-cell-nbsp-activation-by-reprogramming-the-translational-landscape/?sc=rsin /articles/cpeb1-directs-muscle-nbsp-stem-cell-nbsp-activation-by-reprogramming-the-translational-landscape/?sc=rsin Tue, 22 Feb 2022 05:00:55 EST ... through the regulation of p27Kip1 mRNA translation and modulates glioma聽stem cell聽differentiation via regulating Hes1 and Sirt1 translation 36,... may be a potential Aurka downstream target, regulating SC function with regards to聽stem聽cell聽self-renewal聽... Nature Communications /articles/enhanced-germline-nbsp-stem-cell-nbsp-longevity-in-drosophila-diapause/?sc=rsin /articles/enhanced-germline-nbsp-stem-cell-nbsp-longevity-in-drosophila-diapause/?sc=rsin Mon, 14 Feb 2022 08:00:18 EST ... We were surprised to find that GSCs are not maintained in a聽stem聽cell聽state during diapause, even though ovaries can rebound post-diapause to youthful聽stem聽cell numbers, proliferation, and ovary size. This remarkable recovery potential appears聽... Nature Communications /articles/generation-of-the-organotypic-kidney-structure-by-integrating-pluripotent-nbsp-stem-cell-derived-renal-stroma/?sc=rsin /articles/generation-of-the-organotypic-kidney-structure-by-integrating-pluripotent-nbsp-stem-cell-derived-renal-stroma/?sc=rsin Mon, 07 Feb 2022 03:00:08 EST ... Recent progress in聽stem聽cell聽biology has enabled the generation of "organoids" from pluripotent stem cells (PSCs), but most of the currently available organoids lack the organotypic "higher-order structure", in which functional units are distributed at聽... Nature Communications /articles/cholinergic-signals-preserve-haematopoietic-nbsp-stem-cell-nbsp-quiescence-during-regenerative-haematopoiesis/?sc=rsin /articles/cholinergic-signals-preserve-haematopoietic-nbsp-stem-cell-nbsp-quiescence-during-regenerative-haematopoiesis/?sc=rsin Fri, 04 Feb 2022 12:00:41 EST ... to increased CXCL12 expression and haematopoietic聽stem聽cell聽quiescence. Consequently, nicotine exposure increases endosteal haematopoietic聽stem聽cell quiescence in vivo and impairs hematopoietic regeneration after haematopoietic聽... Nature Communications