Latest news from World Journal of Stem Cells on 海角社区 en-us Copyright 2025 海角社区 115 31 / /images/newswise-logo-rss.gif /articles/microvesicles-derived-from-mesenchymal-stem-cells-a-promising-therapeutic-strategy-for-acute-respiratory-distress-syndrome-related-pulmonary-fibrosis5/?sc=rsin /articles/microvesicles-derived-from-mesenchymal-stem-cells-a-promising-therapeutic-strategy-for-acute-respiratory-distress-syndrome-related-pulmonary-fibrosis5/?sc=rsin Mon, 27 Jan 2025 04:50:26 EST Pulmonary fibrosis significantly contributes to the pathogenesis of acute respiratory distress syndrome (ARDS), markedly increasing patient mortality. Despite the established anti-fibrotic effects of mesenchymal stem cells (MSCs), numerous World Journal of Stem Cells /articles/bone-marrow-mesenchymal-stem-cells-promote-uterine-healing-by-activating-the-pi3k-akt-pathway-and-modulating-inflammation-in-rat-models/?sc=rsin /articles/bone-marrow-mesenchymal-stem-cells-promote-uterine-healing-by-activating-the-pi3k-akt-pathway-and-modulating-inflammation-in-rat-models/?sc=rsin Sun, 26 Jan 2025 12:00:49 EST BACKGROUNDUterine injury can cause uterine scarring, leading to a series of complications that threaten women's health. Uterine healing is a complex process, and there are currently no effective treatments. Although our previous studies h World Journal of Stem Cells /articles/extended-protective-effects-of-three-dimensional-cultured-human-mesenchymal-stromal-cells-in-a-neuroinflammation-model/?sc=rsin /articles/extended-protective-effects-of-three-dimensional-cultured-human-mesenchymal-stromal-cells-in-a-neuroinflammation-model/?sc=rsin Sun, 26 Jan 2025 12:00:43 EST BACKGROUNDHuman mesenchymal stromal cells (MSCs) possess regenerative potential due to pluripotency and paracrine functions. However, their stemness and immunomodulatory capabilities are sub-optimal in conventional two-dimensional (2D) cult World Journal of Stem Cells /articles/bridging-bioengineering-and-nanotechnology-bone-marrow-derived-mesenchymal-stem-cell-exosome-solutions-for-peripheral-nerve-injury/?sc=rsin /articles/bridging-bioengineering-and-nanotechnology-bone-marrow-derived-mesenchymal-stem-cell-exosome-solutions-for-peripheral-nerve-injury/?sc=rsin Sun, 26 Jan 2025 12:00:41 EST Peripheral nerve injury (PNI) is a common disease that is difficult to nerve regeneration with current therapies. Fortunately, Zou et al demonstrated the role and mechanism of bone marrow derived mesenchymal stem cells (BMSCs) in promoting World Journal of Stem Cells /articles/protective-activity-of-adipose-derived-stem-cell-extracellular-vesicles-in-ischemia-and-or-reperfusion/?sc=rsin /articles/protective-activity-of-adipose-derived-stem-cell-extracellular-vesicles-in-ischemia-and-or-reperfusion/?sc=rsin Sun, 26 Jan 2025 12:00:29 EST Increasing evidence of the significant clinical value of protection against ischemia/reperfusion injury has contributed to the realization of the independent importance of this approach in improving prognosis and reducing cardiovascular mor World Journal of Stem Cells /articles/melatonin-regulation-and-the-function-of-the-periodontal-ligament-future-perspective-and-challenges/?sc=rsin /articles/melatonin-regulation-and-the-function-of-the-periodontal-ligament-future-perspective-and-challenges/?sc=rsin Sun, 26 Jan 2025 12:00:18 EST The present article reviews the emerging role of melatonin (MT) and the Hippo-Yes-associated protein signaling pathway in periodontal regeneration, highlighting their potential to delay the aging process of periodontal ligament stem cells ( World Journal of Stem Cells /articles/advances-in-human-umbilical-cord-mesenchymal-stem-cells-derived-extracellular-vesicles-and-biomaterial-assemblies-for-endometrial-injury-treatment/?sc=rsin /articles/advances-in-human-umbilical-cord-mesenchymal-stem-cells-derived-extracellular-vesicles-and-biomaterial-assemblies-for-endometrial-injury-treatment/?sc=rsin Sun, 26 Jan 2025 12:00:13 EST Endometrial injury caused by repeated uterine procedures, infections, inflammation, or uterine artery dysfunction can deplete endometrial stem/progenitor cells and impair regeneration, thereby diminishing endometrial receptivity and evident World Journal of Stem Cells /articles/stromal-vascular-fraction-mechanisms-and-application-in-reproductive-disorders/?sc=rsin /articles/stromal-vascular-fraction-mechanisms-and-application-in-reproductive-disorders/?sc=rsin Sun, 26 Jan 2025 12:00:04 EST Stromal vascular fraction (SVF) is a complex mixture derived from adipose tissue, consisting of a variety of cells. Due to its potential for tissue repair, immunomodulation, and support of angiogenesis, SVF represents a promising frontier i World Journal of Stem Cells /articles/immortalization-of-epidural-fat-derived-mesenchymal-stem-cells-in-vitro-characterization-and-adipocyte-differentiation-potential/?sc=rsin /articles/immortalization-of-epidural-fat-derived-mesenchymal-stem-cells-in-vitro-characterization-and-adipocyte-differentiation-potential/?sc=rsin Sun, 26 Jan 2025 12:00:02 EST BACKGROUNDMesenchymal stem cells (MSCs) are promising candidates for regenerative therapy due to their self-renewal capability, multilineage differentiation potential, and immunomodulatory effects. The molecular characteristics of MSCs are World Journal of Stem Cells /articles/interplay-and-therapeutic-implications-of-colorectal-cancer-stem-cells-tumor-microenvironment-and-gut-microbiota/?sc=rsin /articles/interplay-and-therapeutic-implications-of-colorectal-cancer-stem-cells-tumor-microenvironment-and-gut-microbiota/?sc=rsin Thu, 26 Dec 2024 12:00:54 EST This article discusses the interplay between colorectal cancer (CRC) stem cells, tumor microenvironment (TME), and gut microbiota, emphasizing their dynamic roles in cancer progression and treatment resistance. It highlights the adaptabilit World Journal of Stem Cells /articles/dual-role-of-extracellular-vesicles-in-neurodegenerative-diseases/?sc=rsin /articles/dual-role-of-extracellular-vesicles-in-neurodegenerative-diseases/?sc=rsin Thu, 26 Dec 2024 12:00:45 EST Extracellular vesicles (EVs) are cell-to-cell interaction tools that are attracting increasing interest in the literature in two opposing areas. In addition to their role in physiological development, there is growing evidence of their invo World Journal of Stem Cells /articles/preliminary-study-on-the-preparation-of-lyophilized-acellular-nerve-scaffold-complexes-from-rabbit-sciatic-nerves-with-human-umbilical-cord-mesenchymal-stem-cells/?sc=rsin /articles/preliminary-study-on-the-preparation-of-lyophilized-acellular-nerve-scaffold-complexes-from-rabbit-sciatic-nerves-with-human-umbilical-cord-mesenchymal-stem-cells/?sc=rsin Thu, 26 Dec 2024 12:00:35 EST BACKGROUNDThe gold standard of care for patients with severe peripheral nerve injury is autologous nerve grafting; however, autologous nerve grafts are usually limited for patients because of the limited number of autologous nerve sources a World Journal of Stem Cells /articles/mesenchymal-stem-cell-therapy-in-atherosclerosis-a-bibliometric-and-visual-analysis/?sc=rsin /articles/mesenchymal-stem-cell-therapy-in-atherosclerosis-a-bibliometric-and-visual-analysis/?sc=rsin Thu, 26 Dec 2024 12:00:30 EST BACKGROUNDMesenchymal stem cells (MSCs) are capable of self-renewal and differentiation, and extensive studies have demonstrated their therapeutic potential in atherosclerosis (AS). AIMTo conduct a bibliometric analysis of studies on the u World Journal of Stem Cells /articles/exosomes-derived-from-microrna-540-3p-overexpressing-mesenchymal-stem-cells-promote-immune-tolerance-via-the-cd74-nuclear-factor-kappab-pathway-in-cardiac-allograft/?sc=rsin /articles/exosomes-derived-from-microrna-540-3p-overexpressing-mesenchymal-stem-cells-promote-immune-tolerance-via-the-cd74-nuclear-factor-kappab-pathway-in-cardiac-allograft/?sc=rsin Thu, 26 Dec 2024 12:00:22 EST BACKGROUNDHeart transplantation is a crucial intervention for severe heart failure, yet the challenge of organ rejection is significant. Bone marrow mesenchymal stem cells (BMSCs) and their exosomes have demonstrated potential in modulating World Journal of Stem Cells /articles/preliminary-evidence-of-renal-function-improvement-in-chronic-progressive-kidney-disease-using-autologous-cd34-cell-therapy-a-clinical-trial/?sc=rsin /articles/preliminary-evidence-of-renal-function-improvement-in-chronic-progressive-kidney-disease-using-autologous-cd34-cell-therapy-a-clinical-trial/?sc=rsin Thu, 26 Dec 2024 12:00:16 EST BACKGROUNDTo date, no specific treatment has been established to reverse progressive chronic kidney disease (CKD). AIMTo evaluate the safety and efficacy of autologous CD34+ cell transplantation in CKD patients who exhibited a progressive World Journal of Stem Cells /articles/application-of-autophagy-in-mesenchymal-stem-cells/?sc=rsin /articles/application-of-autophagy-in-mesenchymal-stem-cells/?sc=rsin Thu, 26 Dec 2024 12:00:12 EST In this editorial, we have taken an in-depth look at the article published by Wan et al. The study showed that preconditioning mesenchymal stem cells (MSCs) protected them against programmed cell death, and increased their survival rate and World Journal of Stem Cells /articles/innovative-hydrogel-delivery-of-bone-marrow-stromal-cell-derived-exosomes-for-enhanced-bone-healing/?sc=rsin /articles/innovative-hydrogel-delivery-of-bone-marrow-stromal-cell-derived-exosomes-for-enhanced-bone-healing/?sc=rsin Thu, 26 Dec 2024 12:00:11 EST Bone regeneration is a multifaceted process involving the well-coordinated interaction of cellular functions such as the regulation of inflammation, the formation of new blood vessels, and the development of bone tissue. Bone regeneration i World Journal of Stem Cells /articles/bibliometrics-of-trends-in-global-research-on-the-roles-of-stem-cells-in-myocardial-fibrosis-therapy/?sc=rsin /articles/bibliometrics-of-trends-in-global-research-on-the-roles-of-stem-cells-in-myocardial-fibrosis-therapy/?sc=rsin Thu, 26 Dec 2024 12:00:06 EST BACKGROUNDMyocardial fibrosis, a condition linked to several cardiovascular diseases, is associated with a poor prognosis. Stem cell therapy has emerged as a potential treatment option and the application of stem cell therapy has been studi World Journal of Stem Cells /articles/potential-of-ginsenoside-rg1-to-treat-aplastic-anemia-via-mitogen-activated-protein-kinase-pathway-in-cyclophosphamide-induced-myelosuppression-mouse-model/?sc=rsin /articles/potential-of-ginsenoside-rg1-to-treat-aplastic-anemia-via-mitogen-activated-protein-kinase-pathway-in-cyclophosphamide-induced-myelosuppression-mouse-model/?sc=rsin Tue, 26 Nov 2024 12:00:44 EST Aplastic anemia (AA) is a rare but serious condition in which the bone marrow fails to produce sufficient new blood cells, leading to fatigue, increased susceptibility to infection, and uncontrolled bleeding. In this editorial, we review an World Journal of Stem Cells /articles/refining-adipose-derived-stem-cell-isolation-for-optimal-regenerative-therapy/?sc=rsin /articles/refining-adipose-derived-stem-cell-isolation-for-optimal-regenerative-therapy/?sc=rsin Tue, 26 Nov 2024 12:00:42 EST This article highlights the importance of optimizing the techniques used for isolating stromal vascular fraction cells from adipose tissue. Furthermore, by presenting key findings from the literature, it clarifies the effects of refined tec World Journal of Stem Cells